No-Prezan

Drotaverine

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Drotaverine

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No-Prezan

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Veterinary antispasmodic with special dosages and painless administration for convenient and legal use in cats and dogs

Safe use in clinics
Painless administration
Dosage form adapted for cats and dogs
Effective from the second minute

Composition

Pharmacological properties

Indications

Dosage and method of administration

Restrictions

1 ml No-Prezan

drotaverine 20 mg

Please note: The information given on this page is for an informative purpose only. Product characteristics, packaging, label design and overall appearance may vary in different regions. Contact our representatives for more information.

Pharmacological properties

Drotaverine has a powerful antispasmodic effect on smooth muscles due to inhibition of the enzyme phosphodiesterase 4 (PDE 4). Inhibition of the PDE4 enzyme leads to an increase in the concentration of cyclic adenosine monophosphate (CAMP), which inactivates the light chain of myosin kinase (MLCK), which, in turn, leads to relaxation of smooth muscles.

Indications

No-Prezan is used in dogs and cats to relieve smooth muscle spasms associated with the following conditions:

biliary system: conditions of inflammatory origin (cholecystitis, pericholecystitis, cholangitis), cholelithiasis (cholecystolithiasis, choledocholithiasis)
urinary tract: conditions of inflammatory origin (pyelitis, urocystitis, ureteritis, urethritis), urolithiasis (nephrolithiasis, urethrolithiasis, cystolithiasis, ureterolithiasis), bladder spasm (painful tenesmus, idiopathic cystitis)
gastrointestinal tract: conditions of inflammatory origin (gastric and duodenal ulcers, gastritis, enteritis, colitis, irritable bowel syndrome with flatulence), conditions of spastic origin (pylorospasm, achalasia cardia, spastic colitis with constipation)
reproductive system: conditions of inflammatory origin (prostatitis, endometritis, vestibulitis)
to relieve spasmodic pain in the postpartum and postoperative periods, as well as during certain instrumental examinations (bladder catheterization, retrograde urocystography, etc.)

Dosage and method of administration

Indicators	Cats and dogs
Dosage	Single dose of 1-3 mg drotaverine hydrochloride per 1 kg of animal body weight
Method and frequency of administration	Intramuscularly or subcutaneously. It is allowed to divide the daily dose into 2-3 doses
Treatment course	Depending on the severity of the disease, the dosage, frequency and the course of administration can be determined individually by a veterinarian
The daily dose should not exceed 3 mg of drotaverine hydrochloride per 1 kg of animal body weight

Restrictions

Contraindications and special instructions:
Hypersensitivity to sodium bisulfite.
Severe liver or kidney failure.
Severe heart failure.
Glaucoma.
Low blood pressure (arterial hypotension), AV block of II-III degree.