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Pharmacological properties
Doxycycline is a semisynthetic antibiotic that belongs to the 3rd generation of the tetracycline group. Doxycycline inhibits bacterial growth by inhibiting enzymes causing disruption of microbial cell protein synthesis. The drug is effective against gram-positive and gram-negative microbes including:
- Escherichia coli
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Haemophilus spp.
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Pasteurella spp.
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Salmonella spp.
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Staphylococcus spp.
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Streptococcus spp.
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Leptospira spp.
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Chlamydia spp.
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Clostridium perfringens
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Listeria monocytogenes
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Corynebacterium pyogenes
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Rickettsia spp.
-
Mycoplasma spp.
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Indications
Doxylox is prescribed to cattle, small ruminants, pigs to treat infections caused by doxycycline-sensitive microorganisms, including colibacillosis, salmonellosis, pasteurellosis, swine enzootic pneumonia, chlamydia- and staphylococcus-induced diseases, Glasser's disease, and other diseases of bacterial and mycoplasmal etiology.
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Dosage and method of administration
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Animal
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Method of administration
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Dosage
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Treatment period
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Cattle, small ruminants
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Intramuscularly
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1 ml / 10 kg of animal body weight
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Once
If necessary, repeat injection in 48 hours
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|
Pigs
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1 ml / 20 kg of animal body weight
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If the required volume of the drug exceeds 2.5 ml for lambs and piglets, 5 ml for adult pigs, sheep and calves, and 10 ml for cattle, several injections in various injection sites shall be made in order to avoid a possible pain reaction.
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Restrictions
Contraindications and special instructions:
Avoid using the drug simultaneously with penicillin antibiotics and cephalosporins, as well as with calcium drugs due to a possible decrease in its activity.
Avoid using the drug during pregnancy and lactation.
Withdrawal period:
meat: 21 days
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