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Pharmacological properties
Doxycycline belongs to the tetracycline antibiotics. Doxycycline inhibits bacterial growth by inhibiting enzymes causing disruption of microbial cell protein synthesis. It has a bacteriostatic effect on gram-positive and gram-negative microorganisms including:
- Chlamydia spp.
- Clostridium spp.
- Escherichia coli
- Haemophilus spp.
- Leptospira spp.
- Listeria spp.
- Mycoplasma spp.
- Pasteurella spp.
- Salmonella spp.
- Staphylосоccus spp.
- Streptococcus spp.
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Indications
Doxylox OR is used in pigs and poultry to treat and prevent colibacillosis, pasteurellosis, salmonellosis, and staphylococcus infections, mycoplasmosis, chronic respiratory diseases of bacterial etiology, and other infections, caused by doxycycline-sensitive agents.
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Dosage and method of administration
|
Specie
|
Method of administration
|
Dosage
|
Treatment period
|
|
Poultry
|
Orally
|
0.5 - 1 ml/1 l of drinking water
|
3 – 5 days
|
|
Pigs
|
1 ml/10 kg of animal body weight
|
5 days
|
Doxylox OR is administered individually or by a group method. In the case of the group method used, during the treatment period, pigs and poultry should receive water with the drug only. The treatment solution, measured to be consumed within a day, is prepared daily. No rusty drinkers shall be used.
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Restrictions
Contraindications and special instructions:
Avoid using the drug simultaneously with corticosteroids and estrogens, as well as with muscle relaxants. Avoid using Doxylox OR in animals suffering from liver failure, in pregnant and lactating animals. Avoid using the drug in laying hens and replacement chickens less than 14 days before the start of egg laying.
Withdrawal period:
meat: 10 days (pigs), 6 days (poultry)
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