Amoxygard

Аmoxicillin, clavulanic acid

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Аmoxicillin, clavulanic acid

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Amoxygard

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Combined drug based on amoxicillin and clavulanic acid that overcomes resistance to amoxicillin and other β-lactam antibiotics

Extended spectrum of action
Clavulanic acid restores the activity of amoxicillin to resistant pathogens
Highly effective treatment

Composition

Pharmacological properties

Indications

Dosage and method of administration

Restrictions

1 ml Amoxygard

amoxicillin 140 mg

clavulanic acid 35 mg

Please note: The information given on this page is for an informative purpose only. Product characteristics, packaging, label design and overall appearance may vary in different regions. Contact our representatives for more information.

Pharmacological properties

The combination of amoxicillin and clavulanic acid has a broad-spectrum bactericidal activity against most gram-positive and gram-negative microorganisms, including β-lactamase-producing strains:

Actinobacillus lignieresii
Actinobacillus pleuropneumoniae
Actinobacillus spp.
Actinomyces bovis
Actinomyces spp.
Bacillus anthracis
Bacillus spp.
Bacteroides spp.
Bordetella bronchiseptica
Bordetella spp.

Campylobacter spp.
Clostridium spp.
Corynebacterium spp.
Erysipelothrix rhusiopathiae
Erysipelothrix spp.
Escherichia coli
Fusobacterium necrophorum
Fusobacterium spp.
Haemophilus spp.
Klebsiella spp.

Leptospira spp.
Listeria spp.
Moraxella spp.
Pasteurella spp.
Peptostreptococcus spp.
Proteus spp.
Salmonella spp.
Staphylococcus spp.
Streptococcus spp.

Resistance to β-lactam antibiotics is usually associated with the ability of microorganisms to produce β-lactamase, i. e. an enzyme that breaks down the β-lactam ring of the antibiotic before it can affect the bacterium. Clavulanic acid inactivates β-lactamase and thus restores the bacterial sensitivity of bacteria to amoxicillin at concentrations that are easily achieved in the animal tissues by injecting the drug.

Indications

Amoxygard is used in catle for treatment of diseases of bacterial etiology, the pathogens of which are sensitive to a combination of amoxicillin and clavulanic acid: respiratory diseases of bacterial etiology, obstetric-gynecological diseases (metritis, mastitis), surgical diseases, including soft tissue infections (abscesses, phlegmon, furunculosis).

Dosage and method of administration

Specie	Dosage	Method and frequency of administration	Treatment course
Cattle	1 ml/20 kg of b.w.	Intramuscularly, once every 24 hours	3-5 days

Before each use, the vial is thoroughly shaken until a homogeneous suspension is obtained.

It is recommended massaging the injection site after administration of the drug.

Only dry syringes and needles are used to administer the drug.

Restrictions

Contraindications and special instructions:
Avoid using the drug simultaneously with thiamphenicol, chloramphenicol, penicillin group antibiotics, cephalosporins and fluoroquinolones, as well as mixed in one syringe with other drugs.

Withdrawal period:
meat: 42 days
milk: 108 hours