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Pharmacological properties
Doxycycline is a semisynthetic antibiotic that belongs to the 3rd generation of the tetracycline group. Doxycycline inhibits bacterial growth by inhibiting enzymes causing disruption of microbial cell protein synthesis. The drug is effective against gram-positive and gram-negative microbes including:
- Escherichia coli
-
Haemophilus spp.
-
Pasteurella spp.
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Salmonella spp.
-
Staphylococcus spp.
-
Streptococcus spp.
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Leptospira spp.
-
Chlamydia spp.
-
Clostridium perfringens
-
Listeria monocytogenes
-
Corynebacterium pyogenes
-
Rickettsia spp.
-
Mycoplasma spp.
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Indications
Doxylox OR is used in poultry to treat and prevent colibacillosis, pasteurellosis, salmonellosis, and staphylococcus infections, mycoplasmosis, chronic respiratory diseases of bacterial etiology, and other infections, caused by doxycycline-sensitive agents.
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Dosage and method of administration
|
Specie
|
Method of administration
|
Dosage
|
Treatment period
|
|
Poultry
|
Orally
|
0.5 - 1 ml/1 l of drinking water
|
3 – 5 days
|
Doxylox OR is administered individually or by a group method. In the case of the group method used, during the treatment period, poultry should receive water with the drug only. The treatment solution, measured to be consumed within a day, is prepared daily. No rusty drinkers shall be used.
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Restrictions
Avoid using the drug simultaneously with corticosteroids and estrogens, as well as with muscle relaxants. Avoid using Doxylox OR in animals suffering from liver failure, in pregnant and lactating animals. Avoid using the drug in laying hens and replacement chickens less than 14 days before the start of egg laying.
Withdrawal period:
meat: 6 days
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