No-Prezan Tab

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Veterinary antispasmodic with special dosages and adapted taste and smell for good consumption by animals for a comfortable and safe administration in cats and dogs of all weight categories

One of the safest antispasmodics
Easy administration to pets
2 concentrations of drotaverine for convenient and safe administration to animals

Composition

Pharmacological properties

Indications

Dosage and method of administration

Restrictions

1 tab No-Prezan Tab 4 OR 20

drotaverine 4 mg or 20 mg

Please note: The information given on this page is for an informative purpose only. Product characteristics, packaging, label design and overall appearance may vary in different regions. Contact our representatives for more information.

Pharmacological properties

Drotaverine has a powerful antispasmodic effect on smooth muscles due to inhibition of the enzyme phosphodiesterase 4 (PDE 4). Inhibition of the PDE4 enzyme leads to an increase in the concentration of cyclic adenosine monophosphate (CAMP), which inactivates the light chain of myosin kinase (MLCK), which, in turn, leads to relaxation of smooth muscles.

Indications

No-Prezan Tab is used in dogs and cats to relieve smooth muscle spasms associated with diseases of:

biliary system: inflammatory nature (cholecystitis, pericholecystitis, cholangitis), gallstone disease (cholecystolithiasis, cholangiolithia)
urinary tract: inflammatory nature (pyelitis, urocystitis, ureteritis, urethritis), urolithiasis (nephrolithiasis, urethrolithiasis, urocystolithiasis, uroterolithiasis), bladder spasms (painful tenesmus, idiopathic cystitis)
gastrointestinal tract: with inflammation (peptic ulcer of the stomach and duodenum, gastritis, enteritis, colitis, irritable bowel syndrome with flatulence), spastic nature (pylorospasm, achalasia of the cardia, spastic colitis with constipation)
reproductive system: with inflammation (prostatitis, endometritis, vestibulitis)
as well as to relieve spasmodic pain in the postpartum and postoperative periods

Dosage and method of administration

Indicators	Cats and dogs
Dosage	Single dose of 1-3 mg drotaverine hydrochloride per 1 kg of animal body weight
Method and frequency of administration	Perorally individually or mixed with feed. It is allowed to divide the daily dose into 2-3 doses
Treatment course	Depending on the severity of the disease, the dosage, frequency and the course of administration can be determined individually by a veterinarian
The daily dose should not exceed 3 mg of drotaverine hydrochloride per 1 kg of animal body weight

Restrictions

Contraindications and special instructions:

Hypersensitivity to sodium bisulfite
Severe liver or kidney failure
Severe heart failure
Glaucoma
Low blood pressure (arterial hypotension), AV block of II-III degree

No-Prezan Tab

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