Vemelcam 2%

Meloxicam, the active ingredient in the drug, inhibits prostaglandin synthesis, exerting anti-inflammatory, anti-exudative, antipyretic, and analgesic effects.

Its mechanism of action involves selective inhibition of cyclooxygenase-2 (COX-2) enzymatic activity, thereby blocking the synthesis of inflammatory prostaglandins responsible for inflammation, pain, and edema. It has minimal effect on cyclooxygenase-1 (COX-1), thus minimizing the risk of adverse effects (including bleeding, ulcer formation, and impaired renal function). Meloxicam reduces leukocyte infiltration at the site of inflammation, inhibits platelet aggregation, and in animals also suppresses E. coli endotoxin-induced thromboxane B2 production.

Following administration, peak plasma concentrations of the active substance are reached within 1.5-2.5 hours.

Vemelcam 2% is administered to cattle, horses, and pigs as an anti-inflammatory, analgesic, and antipyretic agent for the treatment of:

• Obstetric and gynecological conditions (including mastitis, endometritis, and MMA syndrome)
• Gastrointestinal disorders (including colic)
• Respiratory infections
• Acute and chronic musculoskeletal and soft tissue disorders
• And for relief of pain of various origins.

The product is used as part of comprehensive therapy, taking into account the underlying cause of the disease. Dosage and treatment duration are determined by a veterinary professional based on the animal’s body weight and severity of the condition.

Vemelcam 2% is used once in the following doses:

• cattle: 1 ml of the drug per 40 kg of body weight (subcutaneous or intravenous injection)
• pigs: 1 ml of the drug per 50 kg of body weight (intramuscular injection). If clinically indicated, a second dose may be administered to pigs after 24 hours
• horses: 1 ml of the drug per 33 kg of body weight (intravenous injection)

Contraindications and special instructions:
The drug is not concurrent used with glucocorticosteroids, other nonsteroidal anti-inflammatory drugs, as well as anticoagulants is prohibited.

Use of the drug is prohibited in pregnant and lactating mares.

Withdrawal period:
meat: 15 days (cattle), 5 days (pigs and horses)
milk: 5 days