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Pharmacological properties
D-cloprostenol is a synthetic analogue of prostaglandin F2α (PGF2α). Its use in the luteal phase of the reproductive cycle causes regression of the corpus luteum and creates conditions for the onset of physiological processes associated with a decrease in progesterone levels, the removal of blockade from the hypothalamic-pituitary system and an increase in FSH and LH in the blood of animals, which contributes to the growth of follicles in the ovaries and, as a result, an increase in the level of estrogens in the blood, the appearance of estrus followed by ovulation of mature follicles.
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Indications
Regostenol is used in cows and heifers to normalize reproductive function, for synchronization of the sexual cycle, induction of estrus, treatment of gynecological diseases, including treatment of functional disorders of the ovaries (luteal cyst, persistent corpus luteum), treatment of follicular cysts (in combination with chorionic gonadotropin according to the instructions for use), prevention and treatment of postpartum uterine diseases, termination of pregnancy with fetal pathology.
Please note: The information given on this page is for an informative purpose only. Product characteristics, packaging, label design and overall appearance may vary in different regions.
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Dosage and method of administration
Regostenol is administered by deep intramuscular injection at a dose of 1-2 ml per animal, once, in compliance with the rules of asepsis. The dose in each specific case should be determined by a veterinary specialist based on the anamnesis of animals, depending on the complexity of the pathological process and / or on the time of onset of the clinical effect after administration of the drug.
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Indication
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Method of administration
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Induction of estrus and
synchronization of sexual cycle
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Regostenol is administered to cows and heifers at any phase of the sexual cycle, followed by insemination when signs of estrus appear. Animals that did not come into heat on the 11th day after the first injection are given the drug again in the same dose.
If insemination is carried out without detection of heat, then the animals are inseminated in 72 hours and 96 hours after the second injection.
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Treatment of functional disorders of the ovaries (luteal cyst, persistent corpus luteum)
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Regostenol is administered to cows at the indicated dose after the diagnosis, followed by insemination when signs of sexual estrus appear.
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Treatment of follicular cysts
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After the diagnosis, cows are injected with chorionic gonadotropin and after 11 days Regostenol is administered at the specified dose.
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Prevention and treatment of postpartum uterine diseases (detention of the afterbirth, endometritis, pyometra)
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Regostenol is administered to cows at the indicated dose in combination with agents of etiotropic, pathogenetic and symptomatic therapy.
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In case of chronic endometritis, it is possible to re-administer Regostenol at the same dose after 10-14 days.
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Calving stimulation and prevention of afterbirth retention
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Regostenol is administered to cows at the indicated dose on the day of calving with a weak labor activity, except in cases of large size and incorrect location of the fetus.
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Termination of pregnancy with fetal pathology
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Regostenol is administered to cows at the indicated dose from 1 week to the 5th month of pregnancy. Abortion occurs on 2-7 days after injection.
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Please note: The information given on this page is for an informative purpose only. Product characteristics, packaging, label design and overall appearance may vary in different regions.
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Restrictions
Contraindications and special instructions:
Individual hypersensitivity of the animal to the components of the drug, as well as the period of pregnancy, except in cases of termination of pregnancy with fetal pathology or calving stimulation. It is forbidden to use in animals with diseases of the respiratory or gastrointestinal tract, accompanied by a spastic component.
It can be used during lactation.
Withdrawal period:
meat: 48 hours
milk: 0 hours
Please note: The information given on this page is for an informative purpose only. Product characteristics, packaging, label design and overall appearance may vary in different regions.
Contact our representatives for more information.
