Uteroton

Safeguarding generations
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Propranolol

A non-hormonal drug used to induce labour, to prevent and treat gynecological diseases in animals, and to increase fertility rate.

Stimulation of soft long contractions of the uterine myometrium up to 6 to 8 hours (compared to the classic oxytocin therapy)

Effect on β-adrenoreceptors without blocking the work of the endocrine system as compared with hormone therapy

Increased cattle fertility by 20.4% due to uterine myometrium stimulation after the first insemination

Reduced incidence of uterus subinvolution by about 2 times as compared with oxytocin

Reduced incidence of MMAsyndrome by 1.7 to 2.2 times

Strong anti-stress effect.

  • Description

  • A non-hormonal drug used to induce labour, to prevent and treat gynecological diseases in animals, and to increase fertility rate.

    Uteroton is a transparent colourless solution for injection.

    Packing: 100 mL glass bottles.

    Uteroton
  • Composition
  • Composition
    1 ml
    Uteroton

    5 mg propranolol

  • Pharmacological properties
  • Pharmacological properties

    Uteroton blockades beta-adrenoceptors of myometrium, which promotes endogenic oxytocin activity, thus promoting retraction of uterine smooth muscles and mammary glands. Uteroton is an antagonist of catecholamines; it has a great antistress activity.

  • Indications
  • Indications

    Uteroton is prescribed to stimulate labour in atony and hypotony of the uterus; to prevent the retention of placenta and uterus subinvolution; to increase fertility; for extraction of embryos from donor cows, as a part of combination therapy for the treatment of postpartum endometritis and metritis-mastitis-agalactia (MMA) syndrome in sows.

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  • Dosage and route of administration
  • Dosage and route of administration

    Therapeutic indications

    Dose per animal, ml

    Cow

    Mare

    Sow

    Ewe

    Stimulation of labor activity and prevention of post-parturient complications – once, on the day of delivery

    10

    10

    5

    1

    Retention of afterbirth, thrice with 12 hour intervals

    10

    10

    5

    1

    Treating subinvolution of uterus

    10

    10

    5

    1

    Treatment and prevention of postpartum endometritis

    10

    10

    5

    1

    Prevention of MMA syndrome

    -

    -

    5

    -

    Artificial insemination and mating (in order to increase breeding efficiency)

    5

    5

    5

    1

    Embryo transplantation to donor cows – in 10-15 minutes before embryo flushing

    5

    -

    -

    -

  • Restrictions
  • Restrictions

    CONTRAINDICATIONS

    Avoid using Uteroton in pregnant and young animals.

    Avoid using the drug concurrently with adrenergic agonists, as propranolol prolongs the action of non-depolarizing muscle relaxants. When used concurrently with propranolol, sedatives, and sleeping pills enhance the inhibitory effect on the central nervous system.

    When, concurrently with propranolol, iodine-containing drugs are administered intravenously or intramuscularly, the risk of anaphylactic reactions increases.

    RESTRICTIONS

    No restrictions for meat and milk consumption are set.

    SHELF LIFE

    3 years from the date of manufacture; after first opening - 14 days.

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