Mastitis

Mastitis is inflammation of the mammary gland that occurs in response to the action of pathogenic factors and is characterized by pathological changes both in tissues and mammary gland secretion

Subclinical mastitis is inflammation of the udder where clinical signs are mild or absent. In latent mastitis, the pathological processes in the udder are mild. Sometimes they are characterized by minor mass lesions or edema of the udder, but more often the affected quarters of the udder are reduced in volume with a decreased turgor of its parenchyma. In case of hidden mastitis lactation yield decreases and the quality of milk changes. Diagnosis of subclinical mastitis is based on detection of these changes.

Subclinical mastitis caused by Staphylococcus aureus

If Staphylococcus aureus is identified the additional treatment is carried out at the time of drying off.

1Antibiotics treatment (choice of drugs in accordance with the sensitivity of the defined microflora)	Azitronit	1 ml/20 kg of animal bwt IM at 24-hour interval for 35 days
	Ceftonit Forte	1 ml/30 kg of animal bwt SC, once
2 Application of syringes for a one-step drying off.

Drugs without limitations regarding milk use

** Used for treatment of mastitis diagnosed in service-period

Symptomatic mastitis

Clinical mastitis is inflammation of the udder characterized by hyperemia, a large amount of serous exudate and leukopedesis mainly in interlobular tissue. This kind of inflammation of the udder develops after trauma, due to improper machine milking, as a complication of congestive edema, in case of bacteria penetration through the skin, by hematogenous or lymphogenous route from the genitals and the gastrointestinal tract. The pathogens of mastitis can be streptococci, staphylococci, E. coli, etc.

Five signs of inflammation

• 1. Rubor
  redness
• 2. Tumor
  swelling
• 3. Dolor
  pain
• 4. Calor
  fever
• 5. Functio laese
  functional impairment

1 Antibiotics treatment (choice of drugs in accordance with the sensitivity of the defined microflora)	Ceftonit*	1 ml/50 kg of animal bwt SC at 24-hour interval for 3-5 days
	Lexoflon**	1 ml/30 kg of animal bwt IM at 24-hour interval for 3-5 days
	Amoxygard	1 ml/50 kg of animal bwt SC at 24-hour interval for 3-5 days
	Ceftonit Forte*	1 ml/30 kg of animal bwt SC, once
	Nitox 200	1 ml/10 kg of animal bwt IM, once, repeat in 72 hours if necessary
2 Topical therapy	Mastomicin	10 ml (1 syringe) by intracisternal route per each infected quarter of the udder 4-6 times every 12 hours
3 Symptomatic therapy (in case of body temperature rise)	Flunex	2 ml/45 kg of animal bwt IM or IV at 24-hour interval, for 5 days max.
4 Pathogenetic therapy	Novocaine blocking	0.25-0.5% Novocaine solution at a dose of 150-200 ml depending on the type of blocking.
5 Detoxication	Calcium Borogluconate 20%	0.5 ml/1 kg of animal bwt IM or SC, repeat in 24 hours if necessary
6 Substitutive therapy and stimulation of metabolism	Nitamin	once per 4-8 weeks at a dose of 0.2-0.25 ml/10 kg of animal bwt IM or SC
	Butofan	10-25 ml/animal IM or SC at 24-hour interval, for 4-5 days, repeat the treatment course in 5-14 days if necessary

Products W/O restrictions on milk

** used for treatment of mastitis diagnosed during the service period