Tylosin 50 and 200

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Tylosin

A classical medication with a patented technology of obtaining tylosin as a base to treat animals suffering from bacterial diseases; the sales leader among the injectable macrolide antibiotics.

More stable and effective tylosin base as compared to tylosin tartrate

One of the safest antibiotics

Well-tolerable

Cost-effective treatment course

Short restriction period for meat and milk consumption.

  • Description
  • A classical medication with a patented technology of obtaining tylosin as a base to treat animals suffering from bacterial diseases; the sales leader among the injectable macrolide antibiotics.

    Tylosin is a clear light yellow slightly viscous liquid. Packing: 20, 50, and 100 mL glass bottles filled with a 5% and 20% sterile solution for injections. 

    Tylosin 50 and 200
  • Composition
  • Composition
    1 ml
    Tylosin 50

    50 mg tylosin

    1 ml
    Tylosin 200

    200 mg tylosin

  • Pharmacological properties
  • Pharmacological properties

    Tylosin 50 and Tylosin 200 are macrolide antibacterial drugs. Tylosin is effective against Gram-positive and some Gram-negative bacteria including E.coli., Bacillus anthracis, Pasteurella spp., Haemophilus spp., Leptospira spp., Staphylococсus spp., Streptococcus spp., Erysipelothrix spp., Corynebacterium spp., Mycoplasma spp., Chlamydia spp., Treponema spp., Brachyspira.

    Mode of action: tylosin inhibits bacterial protein synthesis at the ribosomal level. Introduced intramuscularly, the antibiotic quickly resorbs and reaches its maximal concentration in tissues within 1 hour after injection. After that, drug retains its therapeutic concentration for 20 to 24 hours. The drug is excreted from the body mostly with urine and bile; in lactating animals, it can also be excreted from the body with milk.

  • Indications
  • Indications

    Tylosin 50 and Tylosin 200 are prescribed to treat the following diseases:

    • Bronchopneumonia in cattle and small ruminants

    • Mastitis in cattle

    • Infectious agalactia in sheep and goats

    • Secondary infections in viral diseases

    • Bronchopneumonia in pigs

    • Enzootic pneumonia, arthritis, dysentery, and atrophic rhinitis in pigs

    • Secondary infections in viral diseases.

  • Dosage and route of administration
  • Dosage and route of administration

    Tylosin 50 and Tylosin 200 are administered only intramuscularly, once a day, for 5 to 7 consecutive days. With repeated use, the drug shall be administered at several injection sites.

    Recommended doses per 1 kg of animal body weight.

    Animal species

    TYLOSIN 50

    TYLOSIN 200

    Cattle, calves

    0,1-0,2 mL

    0,025-0,05 mL

    Pigs

    0,2 mL

    0,05 mL

    Sheep, goats

    0,2-0,24 mL

    0,05-0,06 mL

    Dogs, cats

    0,1-0,2 mL

    0,025-0,05 mL

    CONTRAINDICATIONS

    Hypersensitivity of an animal to tylosin. Avoid using the drug concurrently with tiamulin, clindamycin, chloramphenicol, penicillins (especially with ampicillin and oxacillin), cephalosporins, and lincomycin, due to a marked decrease in the antibacterial effect of tylosin.

  • Restrictions
  • Restrictions

    Animals can be slaughtered no earlier than 8 days after Tylosin was administered for the last time. In the case of forced slaughter of animals before the established deadlines, the meat can be used for feeding animals.

    Avoid using the milk, obtained during the treatment period and within 4 days after the last injection of the drug was made; however, it can be used for feeding fur-bearing animals.

    SHELF LIFE

    2 years from the date of manufacture; after first opening - 28 days.