Nitox Forte

A confident victory through a single

Oxytetracycline, flunixin

An enhanced NSAID, ex tra long-las ting oxytetracycline, with protective action for 5 days at a single injection

Easier treatment due to extra long-lasting effect (5 days)

Peak concentration reached in 1 hour

Recovery of productive properties within 12 hours

Increased efficacy of antibacterial therapy due to the NSAID included in the drug composition

Description
An enhanced NSAID, ex tra long-las ting oxytetracycline, with protective action for 5 days at a single injection.

Nitox Forte is a clear, green brown to dark brown viscous liquid.

Packing: 100 mLglass bottles.
Composition
Composition

1 ml
Nitox Forte

300 mg oxytetracycline

20 mg flunixin
Pharmacological properties
Pharmacological properties

Nitox Forte belongs to the group of combined antibiotics. Oxytetracycline (a tetracycline antibiotic) has bacteriostatic effect on most Gram-negative and Gram-positive bacteria, including Streptococcus, Staphylococcus, Corynebacterium, Clostridium, Erysipelothrix, Pasteurella, Fusobacterium, Salmonella, Pseudomona, Actinobacteria, Escherichia, Chlamydia, Rickettsia, and Spirochete. Mode of action: oxytetracycline inhibits microbial protein synthesis. Long term (prolonged) action of the drug is due to the complex of oxytetracycline dihydrate and magnesium. Following intramuscular administration, oxytetracycline is absorbed quickly from the injection site and reaches maximum concentrations in organs and tissues in 30 to 50 minutes after administration.

A special pharmaceutical form provides its long-lasting action for 5 days with an antibacterial effect against a wide range of pathogens.

Included in the composition of Nitox Forte, flunixin provides a more pronounced decrease in rectal temperature compared with the oxytetracycline monotherapy.
Indications
Indications

Nitox Forte is prescribed for cattle and pigs to treat acute and chronic diseases of respiratory organs, gastrointestinal tract, urogenital tract, pasteurellosis, peritonitis, arthroempyesis, wound and post-surgery infections, keratoconjunctivitis, foot rot, anaplasmosis, MMA syndrome in sows, and other primary and secondary infections caused by tetracyclinesensitive bacteria

Carried out regarding Nitox Forte used to treat acute tracheobronchitis (complicated with gastroenteritis) in calves, clinical trials showed good results. After a single use of Nitox Forte, recovery was observed within 3 days after one injection. Within the first 24 hours, clinical symptoms disappeared and appetite improved. Comparator drugs were applied twice, while recovery occurred in a 24-hour longer period.

In treating respiratory diseases in calves, the therapeutic efficacy of Nitox Forte was superior compared to the monotherapywith a oxytetracycline-based drug. Complete clinical recovery was observed 2 to 3 days earlier than that at the monotherapy with a drug containing 20% oxytetracycline.
Dosage and route of administration
Dosage and route of administration

The maximum dose to be administered at one site of an adult animal is 10 mL, at that of a young animal - 5 mL.
Restrictions
Restrictions

Cattle and pigs can be slaughtered for human consumption not earlier than 35 days after the last administration of the drug. In the case of forced slaughter of animals before the established deadlines, the meat can be used for feeding carnivores.

SHELF LIFE

2 years from the date of manufacture; after first opening - 28 days.

RECOMMENDATIONS

Nitox Forte is recommended for use with injectors equipped with silicone tubes and gaskets.

Description
Composition
Pharmacological properties
Indications
Dosage and route of administration
Restrictions

An enhanced NSAID, ex tra long-las ting oxytetracycline, with protective action for 5 days at a single injection.

Nitox Forte is a clear, green brown to dark brown viscous liquid.

Packing: 100 mLglass bottles.

Composition

1 ml

Nitox Forte

300 mg oxytetracycline

20 mg flunixin

Pharmacological properties

Nitox Forte belongs to the group of combined antibiotics. Oxytetracycline (a tetracycline antibiotic) has bacteriostatic effect on most Gram-negative and Gram-positive bacteria, including Streptococcus, Staphylococcus, Corynebacterium, Clostridium, Erysipelothrix, Pasteurella, Fusobacterium, Salmonella, Pseudomona, Actinobacteria, Escherichia, Chlamydia, Rickettsia, and Spirochete. Mode of action: oxytetracycline inhibits microbial protein synthesis. Long term (prolonged) action of the drug is due to the complex of oxytetracycline dihydrate and magnesium. Following intramuscular administration, oxytetracycline is absorbed quickly from the injection site and reaches maximum concentrations in organs and tissues in 30 to 50 minutes after administration.

A special pharmaceutical form provides its long-lasting action for 5 days with an antibacterial effect against a wide range of pathogens.

Included in the composition of Nitox Forte, flunixin provides a more pronounced decrease in rectal temperature compared with the oxytetracycline monotherapy.

Indications

Nitox Forte is prescribed for cattle and pigs to treat acute and chronic diseases of respiratory organs, gastrointestinal tract, urogenital tract, pasteurellosis, peritonitis, arthroempyesis, wound and post-surgery infections, keratoconjunctivitis, foot rot, anaplasmosis, MMA syndrome in sows, and other primary and secondary infections caused by tetracyclinesensitive bacteria

Carried out regarding Nitox Forte used to treat acute tracheobronchitis (complicated with gastroenteritis) in calves, clinical trials showed good results. After a single use of Nitox Forte, recovery was observed within 3 days after one injection. Within the first 24 hours, clinical symptoms disappeared and appetite improved. Comparator drugs were applied twice, while recovery occurred in a 24-hour longer period.

In treating respiratory diseases in calves, the therapeutic efficacy of Nitox Forte was superior compared to the monotherapywith a oxytetracycline-based drug. Complete clinical recovery was observed 2 to 3 days earlier than that at the monotherapy with a drug containing 20% oxytetracycline.

Video

Dosage and route of administration

The maximum dose to be administered at one site of an adult animal is 10 mL, at that of a young animal - 5 mL.

Restrictions

Cattle and pigs can be slaughtered for human consumption not earlier than 35 days after the last administration of the drug. In the case of forced slaughter of animals before the established deadlines, the meat can be used for feeding carnivores.

SHELF LIFE

2 years from the date of manufacture; after first opening - 28 days.

RECOMMENDATIONS

Nitox Forte is recommended for use with injectors equipped with silicone tubes and gaskets.

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