Nitox 200

The trust of professionals

Oxytetracycline

The choice of every third veterinarian in Russia

A patented production technology, that allows to achieve the highest quality

Prolonged effect of 72 hours - 1 injection treatment course

Trust of professionals in the veterinary field

Favourable cost of treatment

Description
The most usable** prolonged action oxytetracycline based on magnesium complex.
Appearance: a transparent, slightly viscous brown liquid with a characteristic odor.
The drug is produced as a sterile solution packaged in hermetically sealed 20, 50 and 100 mL vials.
Composition
Composition

1 ml
Nitox 200

200 mg oxytetracycline
Pharmacological properties
Pharmacological properties

Nitox 200 is referred to the group of antibacterial drugs. Oxytetracycline dihydrate, an active substance of Nitox 200, has a bacteriostatic activity against most of Gram-positive and Gram-negative bacteria including streptococci, staphylococci, corynebacteria, clostridia, erysipelothrixes, pasterellae, fusobacteria, salmonellae, pseudomonadae, actinobacteria, escherichia, chlamidiae, rickettsiae, and spirochaete.

Mechanism of action of oxytetracycline is based on the inhibition of microbial protein synthesis. The prolonged activity of the drug is attributed to the magnesium complex of oxytetracycline dehydrate. After intramuscular injection, oxytetracycline dehydrate is quickly absorbed from the injection site and reaches its peak concentration in organs and tissues within 30-50 minutes. The therapeutic level of the antibiotic in blood serum is preserved for 72 hours. Oxytetracycline dehydrate is mainly excreted with bile and urine; in lactating animals, it can also be partially eliminated with milk.
Indications
Indications

Nitox 200 is used in large and small cattle and pigs against infectious diseases caused by microbes sensitive to oxytetracycline, including respiratory diseases of bacterial ethyology: pasteurellosis, athrophic rhinitis, enzootic abortion, mastitis, MAA syndrome, keratoconjunctivitis, foot rot, pyarthrosis, umbilical sepsis, abscess, peritonitis, wound fevers and postpartum infections, anaplasmosis, and secondary infections (of viral diseases).
Dosage and route of administration

Dosage and route of administration

The drug is administered once by deep intramuscular injection.

Type of animal	Dose, ml per 10 kg of animal weight	Maximal amount of drug that can be injected into one place, ml
Bovine cattle	1,0	20,0
Pigs	1,0	10,0
Sheep	1,0	5,0

The animal may experience allergic reactions: erythema and itching at the injection site. These reactions resolve quickly by themselves. If necessary, in the case of overdose or if the animal has a stable allergic reaction to Nitox 200, it is recommended to administer calcium drugs (calcium boron gluconate, calcium chloride) intravenously

Restrictions
Restrictions

Treated animals may be slaughtered for food not earlier than 28 days after the injection of Nitox 200. Meat from animals, forcedly slaughtered before the expiration of the specified term may be used as food for carnivorous animals.
Milk of milking animals may be used as food or be reprocessed no sooner than 7 days after the injection of Nitox 200. The milk produced before the above stated period can be used as animal feed after heat treatment.

Description
Composition
Pharmacological properties
Indications
Dosage and route of administration
Restrictions

The most usable** prolonged action oxytetracycline based on magnesium complex.
Appearance: a transparent, slightly viscous brown liquid with a characteristic odor.
The drug is produced as a sterile solution packaged in hermetically sealed 20, 50 and 100 mL vials.

Composition

1 ml

Nitox 200

200 mg oxytetracycline

Pharmacological properties

Nitox 200 is referred to the group of antibacterial drugs. Oxytetracycline dihydrate, an active substance of Nitox 200, has a bacteriostatic activity against most of Gram-positive and Gram-negative bacteria including streptococci, staphylococci, corynebacteria, clostridia, erysipelothrixes, pasterellae, fusobacteria, salmonellae, pseudomonadae, actinobacteria, escherichia, chlamidiae, rickettsiae, and spirochaete.

Mechanism of action of oxytetracycline is based on the inhibition of microbial protein synthesis. The prolonged activity of the drug is attributed to the magnesium complex of oxytetracycline dehydrate. After intramuscular injection, oxytetracycline dehydrate is quickly absorbed from the injection site and reaches its peak concentration in organs and tissues within 30-50 minutes. The therapeutic level of the antibiotic in blood serum is preserved for 72 hours. Oxytetracycline dehydrate is mainly excreted with bile and urine; in lactating animals, it can also be partially eliminated with milk.

Indications

Nitox 200 is used in large and small cattle and pigs against infectious diseases caused by microbes sensitive to oxytetracycline, including respiratory diseases of bacterial ethyology: pasteurellosis, athrophic rhinitis, enzootic abortion, mastitis, MAA syndrome, keratoconjunctivitis, foot rot, pyarthrosis, umbilical sepsis, abscess, peritonitis, wound fevers and postpartum infections, anaplasmosis, and secondary infections (of viral diseases).

Video

Dosage and route of administration

The drug is administered once by deep intramuscular injection.

Type of animal	Dose, ml per 10 kg of animal weight	Maximal amount of drug that can be injected into one place, ml
Bovine cattle	1,0	20,0
Pigs	1,0	10,0
Sheep	1,0	5,0

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Restrictions

Treated animals may be slaughtered for food not earlier than 28 days after the injection of Nitox 200. Meat from animals, forcedly slaughtered before the expiration of the specified term may be used as food for carnivorous animals.
Milk of milking animals may be used as food or be reprocessed no sooner than 7 days after the injection of Nitox 200. The milk produced before the above stated period can be used as animal feed after heat treatment.

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