Mitrek

Efficiency with no endometritis
КРС - изображение NITA FARM
Препараты
MitrekPhoto1
Cefapirin

Asuspension for intrauterine administration, effective in treating chronic endometritis, with a minimum restriction period for milk consumption.

Restriction period for milk consumption - 1 day

Based on cephalosporin antibiotic

One-shot treatment

Syringe equipped with a catheter for easier insertion.

  • Description
  • Asuspension for intrauterine administration, effective in treating chronic endometritis, with a minimum restriction period for milk consumption.

    Mitrec is a light yellow to yellow suspension.

    Packing: a 19 g plastic syringe, sealed with a protective cap, in a set with catheters for intrauterine administration, disposable gloves for rectal fixation of the cervix

    Mitrek
  • Composition
  • Composition
    1 syringe
    Mitrek

    500mg of сefapirin

  • Pharmacological properties
  • Pharmacological properties

    Mitrec refers to cephalosporin antibiotics.

    Cefapirin has a broad-spectrum bactericidal action against Staphylococcus spp., Streptococcus pyogenes, Pasteurella spp., Proteus mirabilis, Fusobacterium spp., Escherichia coli, Klebsiella spp., Neisseria spp., Pseudo-monas aeruginosa, Enterococcus spp., Salmonella spp., Shigella spp., Haemophilus influenzae, and other pathogenic microorganisms, mainly isolated from subacute and chronic forms of endometritis in cows.

    The bactericidal effect of cefapirin consists in inhibiting the synthesis of the cell wall, which causes the destruction of the cytoplasmic membrane and the death of the bacterial cell. The antibiotic is resistant to the action of the penicillinase enzyme and retains its activity under aerobic and anaerobic conditions.

    Once Mitrec is administered intrauterinally, cefapirin benzathine easily penetrates from the uterine cavity into the endometrium, where it remains in bactericidal concentration for at least 24 hours. Cefapirin benzathine enters the systemic circulation in small amounts; the maximum concentration of antibiotic in blood plasma within 1 to 2 hours after administration is 0.11 to 0.44 µg/mL. The antibiotic is excreted mainly with urine in an unchanged form and in the form of a metabolite, i. e. deacetylcephapirin.

    By the degree of its effect on the animal body, Mitrec refers to low-hazard substances (hazard class 4 as per GOST12.1.007-76).

  • Indications
  • Indications

    Mitrec is prescribed for cows to treat subacute and chronic forms of endometritis of bacterial etiology, as well as hidden forms of endometritis. To cows, the drug is administered in the uterine cavity at a dose of 19 g (i. e. the contents of one syringe). To treat subacute and chronic forms of endometritis, Mitrec is used no earlier than 14 days after calving. If required, the treatment after 7 to 14 days may be repeated with the same dose administered.

    In the case of non-manifest endometritis, Mitrec can cure 93% of the cows after the first application and increase the percentage of fertility by 33%, compared to the use of an intrauterine solution, where the efficiency is 60%. In this case, the solution must be applied at least two times.

    CONTRAINDICATIONS

    Avoid using Mitrec concurrently with other antibiotic-containing drugs for intrauterine administration. Avoid using the drug in pregnant cows.

  • Dosage and route of administration
  • Dosage and route of administration
  • Restrictions
  • Restrictions

    Cattle can be slaughtered for human consumption at least 24 hours after the last application of the drug. In the case of forced slaughter of animals and poultry before the established deadlines, the meat can be used for feeding carnivores.

    The milk, obtained from the cows treated with Mitrec, can be used for human consumption no earlier than 24 hours after the drug was injected for the last time. The milk, taken before the established deadlines, can be used for animal feeding after boiling.

    SHELF LIFE

    3 years from the date of manufacture; the product should not be stored after opening the package

SIMILAR GOODS