As a new generation agent, levofloxacin allows overcoming the microorganisms’ resistance to previous generations fluoroquinolones, including Enrofloxacin.
Levofloxacin penetrates well into the organs and tissues, thus is quickly and almost completely absorbed after parenteral administration. The bioavailability of the active substance is 99%, the concentration in serum reaches its peak within 2 hours after administration, the elimination half-life is 7 hours.
Lexoflon is used in cattle and pigs for treatment of bacterial diseases of the respiratory system, digestive system, obstetric and gynecological diseases (metritis and mastitis), postpartum infections in sows (metritis, mastitis, agalactia), surgical diseases and soft tissue infections (such as abscesses, phlegmon, etc.) caused by pathogens sensitive to levofloxacin, including aerobic Gram-positive microorganisms: Enterococcus spp, Listeria monocytogenes, Staphylococcus spp. (including Staphylococcus aureus), Streptococcus spp; aerobic Gram-negative microorganisms Acinetobacter spp, Campylobacter spp, Enterobacter spp, Escherichia coli, Haemophilus ducreyi, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella spp, Moraxella catarrhalis β+/β-, Morganella morganii, Pasteurella spp, Proteus mirabilis, Proteus vulgaris, Providencia spp, Pseudomonas spp, Salmonella spp, Serratia spp.; anaerobic microorganisms Bacteroides fragilis, Clostridium perfringens, Fusobacterium spp, Peptostreptococcus; other microorganisms: Chlamydia pneumoniae, Chlamydia psittaci, Mycobacterium spp, Mycoplasma pneumoniae, and Ricketsia spp.