An option for rotation with cephalosporins
Overcomes resistance to enrofloxacin
Convenient dosage and route of administration
A broad-spectrum antibiotic for treating cattle with a shorter restriction period for meat and milk consumption.
Lexoflon is a clear greenish yellow to yellow solution.
Packing: 100 mL glass bottles closed with rubber stoppers and sealed with flip-off caps with tamper-evident clips.
150 mg levofloxacin
Levofloxacin is a broad-spectrum fluroquinolone antibiotic with a bactericidal effect against aerobic Gram-positive microorganisms (e. g. Enterococcus spp., Listeria monocytogenes, Staphylococcus spp. (incl. Staphylococcus aureus), and Streptococcus spp.), aerobic Gram-negative microorganisms (incl. Acinetobacter spp., Campylobacter spp., Enterobacter spp., Escherichia coli, Haemophilus ducreyi, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella spp., Moraxella catarrhalis β+/β-, Morganella morganii, Pasteurella spp., Proteus mirabilis, Proteus vulgaris, Providencia spp., Pseudomonas spp., Salmonella spp., and Serratia spp.), anaerobic microorganisms (incl. Bacteroides fragilis, Clostridium perfringens, Fusobacterium spp., Peptostreptococcus), as well against other microorganisms: Chlamydia pneumoniae, Chlamydia psittaci, Mycobacterium spp, Mycoplasma pneumoniae, and Ricketsia spp.
Administered parenterally, levofloxacin is quickly and almost completely absorbed. Levofloxacin easily penetrates into organs and tissues: lungs, bronchial mucosa, phlegm, genitourinary organs, polymorphonucleocytes, and alveolar macrophages.
Lexoflon is prescribed for cattle and pigs to treat bacterial diseases of respiratory organs, digestive system, obstetric-gynecologic diseases like metritis and mastitis, obstetric infections of sows (metritis, mastitis, agalaxia), surgical diseases, including soft tissue infections (abscesses, phlegmons) caused by levofloxacin-sensitive pathogens, including colibacillosis, pasteurellosis, salmonellosis, staphylococcosis, and mycoplasmal infections.
In cattle and pigs, Lexoflon is applied to treat and prevent bacterial infections in epidemiologically concerned farms in case of detection of diseased animals.
Avoid using the drug in animals suffering from hepatic and renal failure, as well as in those hypersensitive to fluoroquinolones. Avoid applying Lexoflon in pregnant animals.
Avoid using the drug concurrently with glucocorticoids due to the increased risk of tendinitis development and/tendon tear, as well as with non-steroidal anti-inflammatory drugs, tetracyclines and macrolides due to the increased toxic effect of levofloxacin. It is not recommended to use levofloxacin concurrently with ethanol
Cattle, sheep and pigs can be slaughterer not earlier than 9 days after the last administration of the veterinary drug. In the case of forced slaughter of animals before the established deadlines, the meat can be used for feeding fur-bearing animals. Milk can be used for human consumption no earlier than 4 days after the drug was administered for the last time. Taken before expiration of the restriction period, the milk can be used for animal feeding after boiling.
2 years from the date of manufacture; after first opening - 28 days.
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