Ivermek

Recognized effectiveness

Ivermectin, vitamin E

A leader among antiparasitic agents, due to a unique combination of ivermectin and vitamin E in the original waterborne formulation, which ensures an increased efficacy of the drug.

Licensed watersoluble formulation

Rapid absorption from the injection site without any irritation occurred

The most active isomers of avermectin included to the composition

Antioxidant effect of vitamin E.

Description
A leader among antiparasitic agents, due to a unique combination of ivermectin and vitamin E in the original waterborne formulation, which ensures an increased efficacy of the drug.

Ivermek is a clear, colourless or slightly opalescent light yellow sterile solution. Packing: 1, 20, 50, 100, 250 and 500 mL hermetically sealed glass bottles.
Composition
Composition

1 ml
Ivermek

10 mg ivermectin

40 mg vitamin E
Pharmacological properties
Pharmacological properties

Ivermek is very effective against larvae and imago of gastrointestinal and pulmonary nematodes as well as larvae of warble flies, bot flies, stomach bot flies, lice, louse flies, and sarcoptoid mites. Mode of action: ivermectin affects the magnitude of the chlorine ion flow passing through neural and muscle cells of a parasite. The main target of the drug are glutamate-sensitive chlorine canals, as well as gamma-aminobutyric acid receptors. By changing the course of the chloride ions flow, the drug disrupts the nerve impulse conduction, which leads to paralysis and subsequent death of parasitic agents.

Ivermek is quickly absorbed from the injection site and spread along the organs and tissues of the animal body ensuring its antiparasitic activity lasting for 10 to 14 days.

If the recommended dosage is observed, the drug does not cause any embrytoxic, teratogenic, or mutagenic effect. The drug is excreted with urine and bile; in lactating animals, it can also be partially excreted with milk. The drug is quickly decomposed in ambient environment.
Indications
Indications

Ivermek is prescribed to prevent and to treat the following animal diseases caused by arachnids, insects, and nematodes:
- cattle: strongylatosis, trichocephalosis, strongyloidosis, thelaziosis, sifunculatosis, hypodermosis, psoroptic mange, sarcoptic mange, and chorioptic mange
- sheep and goats: dictyocaulosis, protostrongyloidosis, mulleriosis, haemonchosis, ostertagiosis, nematodirosis, marshallagiosis, cooperiosis, chabertiosis, oesophagostomiasis, bunostomosis, trichocephalosis, strongyloidosis, mallophagosis, oestrosis, psoroptic mange, and chorioptic mange
- deer: dictyocaulosis, ostertagiosis, nematodirosis, strongyloidosis, trichocephalosis, oedemagenosis, cephenomyosis, and sarcoptic mange
- camels: dictyocaulosis, ostertagiosis, nematodirosis, strongyloidosis, trichocephalosis, and sarcoptic mange
- pigs: trichocephalosis, ascariasis, metastrongylus, esophagostomosis, strongyloidiasis, stephanurus, haematopinus, and sarcoptic mange.
Dosage and route of administration

Dosage and route of administration

The drug is administered to animals intramuscularly, following all aseptic regulations; the injection site for pigs is the neck or inner thigh, while for the other species — the croup and neck. The dose to be injected is as follows:

Animal species	Indications	Route of administration	Dosage	Frequency of administration
Cattle, small ruminants Deer Camels	Nematodoses, arachnoentomos	Intramuscularly	1 mL/50 kg	Once
	Severe cases of sarcoptic mange			Twice, with a 8- to 10-day interval
Pigs	Nematodoses	Intramuscularly	1 mL/33 kg	Once
	Severe cases of sarcoptic mange			Twice, with a 8- to 10-day interval

If the required volume of drug exceeds 10.0 mL, the drug should be injected portionally in various injection sites.

To treat nematode-caused diseases, the drug shall be administered to animals in autumn before transferring them to stables and in spring before transferring them to pastures; to treat gadfly invasions — straight after the end of gadfly swarming season; against arachnidand insect-caused diseases — depending on the results of veterinary observation.

Ivermek shall be first tested in a small group of animals. In case of no complications observed within 3 days, the veterinary drug is administered to the whole livestock.

CONTRAINDICATIONS

Avoid using the drug in milked, contagious, and weak animals, as well as in pregnant animals (if their milk will be used for human consumption) less than 28 days before lactation.

Restrictions
Restrictions

The animals treated with Ivermek can be slaughtered only 28 days after the drug was administered. In the case of forced slaughter of animals and poultry before the established deadlines, the meat can be used for feeding fur-bearing animals. The milk, obtained from treated milked animals, may be used for human consumption no earlier than 28 days after the last dose of Ivermek was administered.

SHELF LIFE

2 years from the date of manufacture; after first opening - 42 days.

Description
Composition
Pharmacological properties
Indications
Dosage and route of administration
Restrictions

A leader among antiparasitic agents, due to a unique combination of ivermectin and vitamin E in the original waterborne formulation, which ensures an increased efficacy of the drug.

Ivermek is a clear, colourless or slightly opalescent light yellow sterile solution. Packing: 1, 20, 50, 100, 250 and 500 mL hermetically sealed glass bottles.

Composition

1 ml

Ivermek

10 mg ivermectin

40 mg vitamin E

Pharmacological properties

Ivermek is very effective against larvae and imago of gastrointestinal and pulmonary nematodes as well as larvae of warble flies, bot flies, stomach bot flies, lice, louse flies, and sarcoptoid mites. Mode of action: ivermectin affects the magnitude of the chlorine ion flow passing through neural and muscle cells of a parasite. The main target of the drug are glutamate-sensitive chlorine canals, as well as gamma-aminobutyric acid receptors. By changing the course of the chloride ions flow, the drug disrupts the nerve impulse conduction, which leads to paralysis and subsequent death of parasitic agents.

Ivermek is quickly absorbed from the injection site and spread along the organs and tissues of the animal body ensuring its antiparasitic activity lasting for 10 to 14 days.

If the recommended dosage is observed, the drug does not cause any embrytoxic, teratogenic, or mutagenic effect. The drug is excreted with urine and bile; in lactating animals, it can also be partially excreted with milk. The drug is quickly decomposed in ambient environment.

Indications

Ivermek is prescribed to prevent and to treat the following animal diseases caused by arachnids, insects, and nematodes:

cattle: strongylatosis, trichocephalosis, strongyloidosis, thelaziosis, sifunculatosis, hypodermosis, psoroptic mange, sarcoptic mange, and chorioptic mange
sheep and goats: dictyocaulosis, protostrongyloidosis, mulleriosis, haemonchosis, ostertagiosis, nematodirosis, marshallagiosis, cooperiosis, chabertiosis, oesophagostomiasis, bunostomosis, trichocephalosis, strongyloidosis, mallophagosis, oestrosis, psoroptic mange, and chorioptic mange
deer: dictyocaulosis, ostertagiosis, nematodirosis, strongyloidosis, trichocephalosis, oedemagenosis, cephenomyosis, and sarcoptic mange
camels: dictyocaulosis, ostertagiosis, nematodirosis, strongyloidosis, trichocephalosis, and sarcoptic mange
pigs: trichocephalosis, ascariasis, metastrongylus, esophagostomosis, strongyloidiasis, stephanurus, haematopinus, and sarcoptic mange.

Video

Dosage and route of administration

Animal species	Indications	Route of administration	Dosage	Frequency of administration
Cattle, small ruminants Deer Camels	Nematodoses, arachnoentomos	Intramuscularly	1 mL/50 kg	Once
	Severe cases of sarcoptic mange			Twice, with a 8- to 10-day interval
Pigs	Nematodoses	Intramuscularly	1 mL/33 kg	Once
	Severe cases of sarcoptic mange			Twice, with a 8- to 10-day interval

If the required volume of drug exceeds 10.0 mL, the drug should be injected portionally in various injection sites.

Ivermek shall be first tested in a small group of animals. In case of no complications observed within 3 days, the veterinary drug is administered to the whole livestock.

CONTRAINDICATIONS

Avoid using the drug in milked, contagious, and weak animals, as well as in pregnant animals (if their milk will be used for human consumption) less than 28 days before lactation.

Restrictions

The animals treated with Ivermek can be slaughtered only 28 days after the drug was administered. In the case of forced slaughter of animals and poultry before the established deadlines, the meat can be used for feeding fur-bearing animals. The milk, obtained from treated milked animals, may be used for human consumption no earlier than 28 days after the last dose of Ivermek was administered.