A thin layer of Ivermek-gel is applied to the affected site (that shall be first cleared from scabs and crust); the dosage is 0.2 to 0.3 mLper 1 kg of anomal bode weight. The drug shall be rubbed slightly into the skin, from the periphery to the center, while covering 1 to 2 cm of border healthy skin. To prevent the drug from being licked away, the treated animal shall be muzzled (or has the jaws fixed with ribbon or tape) for 15 to 20 minutes after application of the drug. The gel shall be applied 2 to 4 times with a 5- to 7-day interval until the treated animal is completely clinically recovered that shall be confirmed by two negative acarologic tests. If the affected area is large, the drug shall be applied twice with a 1-day interval: one bodyhalf on the first day, and the other half - on the other day. If acariasis is complicated with a bacterial infection, it is recommended to apply immunomodulatory and antibacterial drugs as well.
In case of otodectic mane (ear mange), the external auditory canal is first cleaned from scabs and crust with a sponge saturated with Ivermectin-gel; after that 0.5 to 2.0 mL (depending on the animal body weight) of Ivermectin-gel shall be applied to each ear. In order to apply Ivermectin-gel to the whole surface of the ear and auditory canal, the ear shall be folded in half and then downward and slightly massaged. The drug is applied once or twice with 5- to 7-day interval. If necessary, the treatment can be repeated. The drug must always be applied to both ears, even if only one ear is affected by otodectic mange. In severe cases of the disease (when it is complicated with otits), it is recommended to administer anti-bacterial and anti-inflammatory drugs.
Avoid applying Ivermek-gel concurrently with other topical insecticide and acaricidal drugs, as well as with antiparasitic drugs containing macrocyclic lactones. Hypersensitivity of an animal to the drug components. Avoid using the drug in animals suffering from contagious diseases, as well as in recovering or debilitated animals.