As a preventative measure, one suppository is administered once following afterbirth, abortion, or aided labour; as a treatment measure - one suppository, twice, with a 24- to 48-hour interval. In special cases, the treatment is continued until the animal is fully recovered. Suppositories are introduced into uterine cavity by hand (protected by polyethylene disposable glove). Before application of Iodopen, vulva and tailhead have to be cleansed first.
Due to the foaming basis of the drug, after administration of one suppository, at least 300 mL of foam is formed to ensure the maximum contact of the active ingredient with the endometrium.
When the cervix is closed and it is impossible to introduce the drug in the form of a suppository, it is recommended to use a solution. To prepare the solution, one Iodopen suppository is dissolved in 150 to 200 mL of preheated to 40 °C sterile saline or water. Destruction of the foam is done mechanically or by using defoamers (ethyl alcohol). The resulting solution is introduced into a Janet's syringe or Esmarch's irrigator. The solution shall be administered slowly intrauterinally, using a catheter for artificial insemination or using a 20 to 25 cm silicone tube 0.5 cm in diameter, equipped with a polystyrene pipette. The treatment is carried out once a day, until recovery.
In order to increase the contractive activity of the uterus and accelerate evacuation of exudate, Iodopen is recommended to be used with Uteroton. Uteroton is administered intramuscularly, 5 mL per animal immediately after the first administration of Iodopen.
The drug shall be stored in a dry place, at a temperature of 4 to 20°C.