Instruction for use of Fulgard

I. General information

1. Fulgard is a disinfecting agent for compulsory and preventive disinfection of veterinary supervision objects in the form of solution.

Fulgard is a clear light yellow to brown-yellow liquid with a weak characteristic smell, easily mixable with water in any proportions.

Fulgard is available in 1 L plastic bottles or in 5 or 20 L plastic canisters with screw caps and first opening control clips.

2. Fulgard disinfecting agent is stored in sealed original separately from food and feed, in a dry place, protected from direct sunlight, storage temperature range: -20°С to +25°С; a short-term (no more than 3 months) storage is allowed at a temperature up to +50°С.

Shelf-life of the agent under the specified conditions is 3 years from the date of manufacture. Shelf-life of the working solutions – 30 days.

The use of the agent Fulgard after the expiration date is prohibited.

3. The agent is intended to be used in veterinary disinfecting practice by specialists of organizations involved in disinfecting activity and by individuals in private farms; for compulsory and preventive disinfection of veterinary supervision objects and prevention of animal infectious diseases, including those caused by agents of viral nature.

4. Fulgard should be kept out of reach of children.

5. Unused disinfecting agent should be disposed of in accordance with the applicable legislation.

6. Fulgard can be transported by any means of transport in the original package according to the cargo transportation rules.

II. Сomposition

7. 1 mL of Fulgard disinfecting agent contains a composition of two quarternary ammonium compounds (210 mg of alkyl dimethylbenzylammonium chloride and 30 mg of didecyldimethylammonium chloride), 250 mg of glutaric dialdehyde, 30 mg of isopropanol as active substances, and excipients: purified water – up to 1 ml.

III. Pharmacological properties

8. Fulgard has bactericidal effect against Gram-positive and Gram-negative bacteria, virucidal activity (including against African swine fever virus and classical swine fever virus) and fungicidal activity (including against sporogenous forms, yeasts and molds). The agent is effective against pathogens of I-IV resistance groups.[1] The mechanism of action involves disruption of redox processes in the microbial cell by way of reacting with amine groups of microorganisms’ proteins.   

9. By the degree of its effect on the body, Fulgard is classified as a moderate-risk substance (III substance hazard category according to the GOST 12.1.007-76). The agent does not accumulate in the body. It does not have local irritative and sensitizing effect in the recommended dose. Fulgard working solutions do not have corrosive activity, do not damage the material of surfaces treated, do not cause metal corrosion (does not deteriorate metal, plastic, rubber and other materials).




IV. Administration procedure

10. Fulgard is used for compulsory and preventive disinfection of veterinary supervision objects, including:

– animal, poultry and fur farm facilities, process equipment inside them, auxiliary objects (including incubator houses, egg-handling plants), dairy blocks and feeding centers, sanitary appliances, diseased animal slaughter houses, slaughter rooms and slaughterhouses, open objects (ramps, docks, platforms), packages and uniforms;

– production areas, process equipment and territory of biological, feeding, processing industry enterprises, as well as packages, uniforms and animal care items;

– vehicles (including road, railroad, water and air transport used for transportation of animals and birds, as well as raw materials and animal products);

– veterinary clinics (stations), laboratories, vivariums, circuses and zoos.

Disinfection is performed using small-drop moistening, applying foam, dipping or wiping the surfaces being disinfected with water-based (working) solution. Treatment is performed without animals, slaughter products and animal products manually, by soaking or using disinfecting machines, foam-generating or sprinkling equipment, using aerosol or hot or cold foggers. Aerosol disinfection is performed in a tightly closed and sealed area with ventilation turned off.

Object

Treatment method

Type of disinfection

Concentration of the solution (according to the agent), %

Minimal consumption of working solution for treatment of m2 of the surface

Exposure, min

smooth

rough

Animal, poultry and fur farm facilities, their territories and auxiliary objects, veterinary clinics (stations), laboratories, vivariums, circuses and zoos, production areas and territory of biological, feeding, processing industry enterprises; vehicles used to transport animals and birds, as well as raw materials and animal products

small-drop moistening, foam application, aerosol application, surface wiping

preventive

0.15

250 mL/m2

350 mL/m2

20/30

compulsory treatment in case of African swine fever *2

0.30

300 mL/m2

30

necessary (see cl. 8)

0.30

200 mL/m2

400 mL/m2

180

compulsory during special danger infections3

1.0

200 mL/m2

400 mL/m2

180

aerosol

30

2,5 mL/m3

360

Process equipment, package, uniform, animal care items see cl. 13)

dipping, soaking, surfaces wiping

preventive

0.15

-

-

20

compulsory treatment in case of African swine fever*2

0.30

-

-

30

necessary (see cl. 8)

0.30

-

-

180

compulsory during special danger infections3

1.0

-

-

180

Disinfectant barriers, disinfectant baths

(see cl. 14)

contact treatment

preventive, compulsory

0.60 (1,3-2% - in winter)

antifreezes are added in winter time. The disinfecting agent is replaced as and when required, at least 2 times per 7 days.

*African Swine Fever

11. Before disinfection, the premises and equipment must be mechanically cleaned and washed.

Working solutions should be prepared according to the concentration required for disinfection purposes, by adding necessary amounts of the agent to pipe water, the temperature of which is 8-25°С. When the concentration of working solution is calculated, the agent is taken as 100%.

The amount of Fulgard necessary to prepare working solutions:

– preventive disinfection: 1.5 mL of the agent per 998.5 ml of water;

– compulsory disinfection (disinfection in case of African Swine fever*[1]): 3.0 mL of the agent per 997.0 mL of water;

– compulsory disinfection during Special Danger Infections[2]: 10.0 mL of the agent per 990.0 mL of water;

– aerosol disinfection: 300 mL of the agent per 700 mL of water.

12. Disinfection of livestock houses is performed in the absence of animals. At the end of the predetermined disinfection exposure, the places accessible by animals, where the remainders of the disinfecting agent can possibly accumulate (including feed boxes, drinking bowls and other surface areas), are rinsed with water. It is not required to rinse the remainders of the disinfecting agent from other surfaces. Animals can enter the premises after ventilation.

13. Local disinfection of separate, animal-free bays, cages, equipment units, stock and surface areas is possible provided proper ventilation, as well as absence of people and animals in the close vicinity to the surfaces treated is ensured. Treatment shall be performed with 0.15% Fulgard solution using spray, foam generation method, soaking or wiping the surface.

14. Disinfectant barriers or disinfectant baths are filled with 0.6% Fulgard solution; in winter, it can be up to 1.3-2% with the addition of antifreezes. Disinfecting solution shall be replaced as and when necessary, at least 2 times per 7 days.

15. Used Fulgard working solutions are discarded into the dung pit together with dung or poured into the industrial sewage.

16. The quality of disinfection is controlled according to the method described in the «Rules for conducting disinfection and disinvasion of state veterinary inspection objects» (2002) in force. Sterile water is used as a neutralizing agent.

17. Fulgard is not compatible with anionic surface-active agents and their solutions. It is recommended to prepare Fulgard working solution based on the 30% ethylene glycol water solution in order to use it at a temperature below zero (up to -20°С).

V. Special precautions for use

IV. Special precautions for use

18. Children, pregnant and nursing women shall never perform the treatment! People with skin diseases and hypersensitivity to chemical agents must apply the agent with caution.

19. All works for preparation of working solutions and application of Fulgard must be performed using protective clothing (protective coat or an overall, rubber protection shield, rubber boots, rubber gloves, gastight goggles, face mask RPG-67; RU-60 with type А insert tube or a gas mask set). It is prohibited to drink, smoke and eat while handling the agent. Wash your hands with soap and water after handling the agent.

20. Use of the empty bottles of Fulgard for domestic purposes is prohibited; they must be disposed of along with household waste.

21. Avoid the disinfecting agent getting inside the body, on the skin, eye mucosa, respiratory organs and mucous membranes. If Fulgard contacts the skin, rinse it with plenty of water with soap. If ingested, it is necessary to drink several cups of water with 10-15 tablets of activated carbon. Do not cause vomiting. If any signs of poisoning appear, seek medical help.

22. If Fulgard contacts the eyes, rinse them with water immediately and seek medical help.

23. If any signs of poisoning (dizziness, nausea, weakness) appear during or after work with Fulgard, seek medical help immediately and show the agent’s label.

24. During emergency situations, accidental damage of the package, the spilled agent shall be deactivated using personal protection equipment: a protective coat or an overall, rubber protection shield, rubber boots, face mask RU-60-М, RPG-67 with type А insert tube or a GP-5 gas mask set, rubber or plastic gloves, protective goggles. The spilled agent shall be neutralized with lime hydrate or lime chloride, adsorbed with blotting material (sand, soil, silica gel) and collected into a container for destruction. Soil contaminated with the agent is poured over with 5% solution of soda ash, left for 6-12 hours, then dug over again.