Florox

When others are powerless
КРС - изображение NITA FARM
Свиньи - изображение NITA FARM
FloroxPhoto1
Florfenicol

One of the most affordable professional antimicrobial florfenicol-based drugs with a prolonged action against respiratory diseases in calves and piglets.

Designed specifically for veterinary medicine

Reduced mortality rate in young animals and stable weight gain due to the quick effect of the drug

Increased bioavailability.

  • Description
  • One of the most affordable professional antimicrobial florfenicol-based drugs with a prolonged action against respiratory diseases in calves and piglets.

    Florox is a clear light yellow to dark yellow liquid.

    Packing: 100 mL glass bottles filled with a sterile solution.

    Florox
  • Composition
  • Composition
    1 ml
    Florox

    300 mg florfenicol

  • Pharmacological properties
  • Pharmacological properties

    Florfenicol is a thiamphenicol derivative, where the hydroxyl group is substituted with fluorine. Florfenicol has a bacteriostatic effect: it binds with the 70S ribosomal subunit in the bacterial cell protoplasm, thus blocking peptidyl transferase, which leads to the inhibition of protein synthesis in ribosomes of the sensitive microbial cell.

    The drug is active against acetyl transferase-producing bacteria resistant to chloramphenicol. Florfenicol has a broad-spectrum antibacterial activity against Staphylococcus spp., Streptococcus spp., Escherichia coli, Actinobacillus pleuropneumoniae, Pasteurella spp., Bordetella bronchiseptica, Haemophilus spp., Fusobacterium necrophorum, Klebsiella pneumoniae, as well as against mycoplasma M. hyopneumoniae and M. hyorhinis. Administered parenterally, florfenicol is quickly absorbed and distributed among most organs and tissues of the animal. It reaches its peak serum concentration in 30 to 90 minutes and remains at the therapeutic level for at least 48 hours.

    The antibiotic is excreted from the body unchanged and as metabolites mostly with urine and partially with feces

  • Indications
  • Indications

    Florox is prescribed for cattle and pigs to treat bacterial diseases caused by florflenicolsensitive etiological agents. 

    • In cattle: respiratory diseases (caused by Pasteurella multicida, Klebsiella pneumoniae, Streptococcus pneumoniae, Haemophilus somnus), necrobacillosis, contagious keratoconjunctivitis (caused by Moraxella bovis)

    • In pigs: respiratory diseases including pleuropneumonia (caused by Actinobacillus pleuropneumoniae and/or Haemophilus parasuis, Pasteurella multоcida, M. hyopneumoniae, M. hyorhinis) and atrophic rhinitis.

  • Dosage and route of administration
  • Dosage and route of administration

    In cattle, 1 mL per 15 kg of animal body weight (20 mg of florflenicol per 1 kg) shall be administered intramuscularly twice with a 48-hour interval or 2 mL per 15 kg of animal body weight (40 mg of florflenicol per 1 kg) once subcutaneously.

    In pigs, 1 mL per 20 kg of animal body weight (15 mg of florflenicol per 1 kg) shall be administered intramuscularly in the neck area twice with a 48-hour interval. No more than 10 mLof Florox can be injected to one injection site.

    CONTRAINDICATIONS

    Avoid using Florox concurrently with thiamphenicol and chloramphenicol; avoid mixing it with other medical drugs in one syringe. Avoid using Florox in pregnant and lactating animals.

  • Restrictions
  • Restrictions

    Treated cattle can be slaughtered for human consumption no earlier than 34 days, pigs - no earlier than 14 days after intramuscular administration and 42 days after subcutaneous administration of Florox. In the case of forced slaughter of animals before the established deadlines, the meat can be used for feeding fur-bearing animals.

    SHELF LIFE

    2 years from the date of manufacture; after first opening - 30 days