Clozatrem

Reliable protection against parasites
КРС - изображение NITA FARM
МРС - изображение NITA FARM
ClozatremPhoto1
Closantel

A professional drug to treat and prevent helminthiasis and gadfly invasions in cattle and small ruminants.

Maximum efficacy in treating fascioliasis

Treatment of nematosis and gadfly invasions

Directed action of the injectable solution.

  • Description
  • A professional drug to treat and prevent helminthiasis and gadfly invasions in cattle and small ruminants.

    Clozatrem is a clear pale yellow to yellow green liquid. Packing: 100 and 250 mL glass bottles filled with a sterile solution.

    Clozatrem
  • Composition
  • Composition
    1 ml
    Clozatrem

    50 mg closantel

  • Pharmacological properties
  • Pharmacological properties

    Closantel is a salicylamide derivative and has a broad spectrum of antiparasitic action. It is very effective against mature and immature nematodes including Haemonchus spp., Nematodirus spp., Trichostrongylus spp., Ostertagia spp., Oesophagostomum radiatum, Bunostomum spр., and Chabertia ovis; mature and immature Fasciola hepatica and Fasciola gigantica (trematodes); as well as larvae of gadflies including Hypoderma bovis, Hypoderma lineatum, and Oestrus ovis being parasites in cattle and small ruminants.

    Mode of action: closantel affects the processes of phosphorylation and electron transfer, thus causing metabolism disruption and death of parasitic agents.

    After parenteral administration of the drug, closantel is quickly absorbed from the injection site and distributed along the organs and tissues of the animal body; concentration of closantel reaches its peak values in blood after 10 to 12 hours and remains in the blood at a therapeutic level for up to 10 days after injection. Closantel is eliminated unchanged mostly with bile; in lactating animals, it can also be partially excreted in milk.

  • Indications
  • Indications

    Clozatrem is prescribed to prevent and to treat the following diseases: in cattle—haemonchosis, oesophagostomiasis, bunostomosis, trichostrongylosis, ostertagiosis, fasciolasis, and hypodermosis; in sheep and goats—haemonchosis, nematodyrosis, trichostrongylosis, chabertiosis, bunostomosis, oesophagostomiasis, fasciolasis, and oestrosis.

  • Dosage and route of administration
  • Dosage and route of administration

    The drug shall be administered to animals once in accordance with all aseptic and antiseptic rules:

    • to cattle, Clozatrem shall be administered intramuscularly or subcutaneously at a dose of 0.5 mL per 10 kg of animal body weight (i. e. 2.5 mg of API/kg) to treat nematodosis and fasciolasis; 1 mL per 10 kg of animal body weight (i. e. 5.0 mg of API/kg) to treat hypodermatosis

    • to sheep and goats, Clozatrem shall be applied subcutaneously at a dose of 0.5 mL per 10 kg of animal body weight (i. e. 2.5 mg of API/kg) to treat nematodosis and oestrosis; 1 mL per 10 kg of animal body weight (i. e. 5.0 mg of API/kg) to treat fasciolasis. If the required drug volume exceeds 20 mL in adult cattle and 10 mL in sheep, goats, and calves, several injections in different injection sites shall be made in order to avoid any possible pain reaction. Prior to mass treatment with Clozatrem, each drug batch shall be first tested in a small group of animals (5 to 7 animals) of different fatness. If no complications occurred within 3 days, the drug is used throughout the livestock. Animals shall receive therapeutic treatment against helminthes, if medically required; animals shall receive preventive treatment against helminthes before transferring them to stables and in spring before transferring to pastures; against gadfly invasions - straight after the end of gadfly swarming season and in spring (February - March).

    CONTRAINDICATIONS

    Avoid using Clozatrem in milked animals, as well as in cows, sheep, goats, less than 30 days before calving or lambing, as the drug is excreted with milk. Avoid using Clozatrem in the animals suffering from contagious diseases, as well as in weakened or debilitated animals. Avoid using the drug concurrently with organochlorine and organophosphorus insecticides. 

  • Restrictions
  • Restrictions

    Treated animals can be slaughtered for human consumption no earlier than 28 days after the last injection of Clozatrem was administered. In the case of forced slaughter of animals and poultry before the established deadlines, the meat can be used for feeding fur-bearing animals.

    SHELF LIFE

    3 years from the date of manufacture; after first opening - 28 days.

SIMILAR GOODS
Ricazol. Photo

Ricazol

Antiparasitic
composition
100 mg ricobendazole
composition
100 mg ricobendazole
Meradok. Photo

Meradok

Antiparasitic
composition
10 mg doramectin
composition
10 mg doramectin
Levamisol 75. Photo

Levamisol 75

Antiparasitic
composition
75 mg levamisole
composition
75 mg levamisole
Ivermek-spray. Photo

Ivermek-spray

Antiparasitic
composition
2,5 mg ivermectin
20 mg lidocaine
5 mg dexpanthenol
0,5 mg chlorhexidine
composition
2,5 mg ivermectin
20 mg lidocaine
5 mg dexpanthenol
0,5 mg chlorhexidine
Ivermek-gel. Photo

Ivermek-gel

Antiparasitic
composition
1 mg ivermectin
15 mg panthenol
50 mg lidocaine
composition
1 mg ivermectin
15 mg panthenol
50 mg lidocaine
Ivermek OR. Photo

Ivermek OR

Antiparasitic
composition
10 mg ivermectin
40 mg vitamin E
composition
10 mg ivermectin
40 mg vitamin E
Ivermek. Photo

Ivermek

Antiparasitic
composition
10 mg ivermectin
40 mg vitamin E
composition
10 mg ivermectin
40 mg vitamin E
Cyflunit Flock. Photo

Cyflunit Flock

Antiparasitic
composition
1,13 mg cyfluthrin
composition
1,13 mg cyfluthrin
Cyflunit. Photo

Cyflunit

Antiparasitic
composition
10 mg cyfluthrin
composition
10 mg cyfluthrin
Alvet suspension. Photo

Alvet suspension

Antiparasitic
composition
100 mg albendazole
composition
100 mg albendazole
Alvet. Photo

Alvet

Antiparasitic
composition
200 mg albendazole
composition
200 mg albendazole