Maximum efficacy in treating fascioliasis
Treatment of nematosis and gadfly invasions
Directed action of the injectable solution.
A professional drug to treat and prevent helminthiasis and gadfly invasions in cattle and small ruminants.
Clozatrem is a clear pale yellow to yellow green liquid. Packing: 100 and 250 mL glass bottles filled with a sterile solution.
50 mg closantel
Closantel is a salicylamide derivative and has a broad spectrum of antiparasitic action. It is very effective against mature and immature nematodes including Haemonchus spp., Nematodirus spp., Trichostrongylus spp., Ostertagia spp., Oesophagostomum radiatum, Bunostomum spр., and Chabertia ovis; mature and immature Fasciola hepatica and Fasciola gigantica (trematodes); as well as larvae of gadflies including Hypoderma bovis, Hypoderma lineatum, and Oestrus ovis being parasites in cattle and small ruminants.
Mode of action: closantel affects the processes of phosphorylation and electron transfer, thus causing metabolism disruption and death of parasitic agents.
After parenteral administration of the drug, closantel is quickly absorbed from the injection site and distributed along the organs and tissues of the animal body; concentration of closantel reaches its peak values in blood after 10 to 12 hours and remains in the blood at a therapeutic level for up to 10 days after injection. Closantel is eliminated unchanged mostly with bile; in lactating animals, it can also be partially excreted in milk.
Clozatrem is prescribed to prevent and to treat the following diseases: in cattle—haemonchosis, oesophagostomiasis, bunostomosis, trichostrongylosis, ostertagiosis, fasciolasis, and hypodermosis; in sheep and goats—haemonchosis, nematodyrosis, trichostrongylosis, chabertiosis, bunostomosis, oesophagostomiasis, fasciolasis, and oestrosis.
The drug shall be administered to animals once in accordance with all aseptic and antiseptic rules:
to cattle, Clozatrem shall be administered intramuscularly or subcutaneously at a dose of 0.5 mL per 10 kg of animal body weight (i. e. 2.5 mg of API/kg) to treat nematodosis and fasciolasis; 1 mL per 10 kg of animal body weight (i. e. 5.0 mg of API/kg) to treat hypodermatosis
to sheep and goats, Clozatrem shall be applied subcutaneously at a dose of 0.5 mL per 10 kg of animal body weight (i. e. 2.5 mg of API/kg) to treat nematodosis and oestrosis; 1 mL per 10 kg of animal body weight (i. e. 5.0 mg of API/kg) to treat fasciolasis. If the required drug volume exceeds 20 mL in adult cattle and 10 mL in sheep, goats, and calves, several injections in different injection sites shall be made in order to avoid any possible pain reaction. Prior to mass treatment with Clozatrem, each drug batch shall be first tested in a small group of animals (5 to 7 animals) of different fatness. If no complications occurred within 3 days, the drug is used throughout the livestock. Animals shall receive therapeutic treatment against helminthes, if medically required; animals shall receive preventive treatment against helminthes before transferring them to stables and in spring before transferring to pastures; against gadfly invasions - straight after the end of gadfly swarming season and in spring (February - March).
Avoid using Clozatrem in milked animals, as well as in cows, sheep, goats, less than 30 days before calving or lambing, as the drug is excreted with milk. Avoid using Clozatrem in the animals suffering from contagious diseases, as well as in weakened or debilitated animals. Avoid using the drug concurrently with organochlorine and organophosphorus insecticides.
Treated animals can be slaughtered for human consumption no earlier than 28 days after the last injection of Clozatrem was administered. In the case of forced slaughter of animals and poultry before the established deadlines, the meat can be used for feeding fur-bearing animals.
3 years from the date of manufacture; after first opening - 28 days.
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If this program is not available, then please write to us directly from your mobile phone in Viber or WhatsApp at the number
+7 965 880-47-56.
