Amoxygard WS

Protected amoxicillin
Свиньи - изображение NITA FARM
Птица - изображение NITA FARM
Препараты
Amoxygard WSPhoto1
Amoxicillin, clavulanic acid

A combined water-soluble drug based on amoxycillin and clavulanic acid that works against the resistance to β-lactam antibiotics.

Protected complex of clavulanic acid and amoxicillin

Nanostructure that retains the active form of active substances

Broad spectrum due to synergy between drug components.

  • Description
  • A combined water-soluble drug based on amoxycillin and clavulanic acid that works against the resistance to β-lactam antibiotics.

    Amoxygard WS is a light yellow to yellow powder.

    Packing: 1 kg bags made of a composite material based on aluminum foil.

    Amoxygard WS
  • Composition
  • Composition
    1 g
    Amoxygard® WS

    500 mg amoxicillin

    125 mg clavulanic acid

  • Pharmacological properties
  • Pharmacological properties

    Amoxicillin is a broad-spectrum penicillin antibiotic, having bactericidal effect on most Gram-positive and Gram-negative microorganisms, including β-lactamase producing strains: Escherichia coli, Salmonella spp., Pasteurella spp., Clostridium spp., Staphylococcus spp., Erysipelothrix rhusiopathiae, Bordetella bronchiseptica, Haemophilus spp., Streptococcus spp., Klebsiella spp., Bacillus anthracis, Campylobacter spp., and Actinomyces (Corynebacterium) pyogenes.

    Amoxicillin is a penicillin family antibiotic.

    Mode of action: the drug disrupts the process of mucopeptide (a component of microbial cell wall) synthesis by inhibiting transpeptidase and carboxypeptidase activity, which leads to disruption of osmotic balance and destruction of the microbial cell. Clavulanic acid, inhibiting β-lactamase, protects amoxicillin from the enzyme.

    The drug has a rapid bactericidal effect, while combined amoxicillin and clavulanic acid formulation affects penicillin-resistant microorganisms, among others.

    Amoxicillin and clavulanic acid are well absorbed from the gastrointestinal tract and penetrate into the organs and tissues of the animal body, with their therapeutic concentrations retained for at least 12 hours after Amoxigard WS was administered; they are excreted mainly with urine and partially with bile, mainly in an unchanged form. Feed intake does not significantly affect the absorption of the drug.

  • Indications
  • Indications

    Amoxygard WS is prescribed for pigs and poultry to prevent and to treat diseases of bacterial etiology, including colibacteriosis, salmonellosis, pasteurellosis, bronchopneumonia, necrotizing enteritis, campylobacteriosis, staphylococcosis, Glasser’s disease, streptococcosis, actinobacillary pleuropneumonia, atrophic rhinitis, urinary infections, skin and soft tissue infections caused by pathogens sensitive to the components of the medication.

  • Dosage and route of administration
  • Dosage and route of administration

    Amoxygard WS is administrated orally for 3 to 5 days:

    Species

    Route of administration

    Dosage

    Treatment regimen

    Note

    Pigs

    Orally with drinking water, milk, or feed

    0,8 to 2 g/100 kg of the animal body weight

    Two times a day, 3 to 5 days

    Amoxigard WS is completely dissolved, when introducing 20 g of the drug in at least 7 liters of water. During treatment, the treatment solution should be the only source of drinking

    Poultry

    Orally with drinking water

    4 g/100 kg of the bird body weight

    3 to 5 days

    CONTRAINDICATIONS

    Hypersensitivity of an animal to penicillin family antibiotics and to other drug components. Avoid using Amoxigard WS in laying hens (with eggs used for human consumption) and in replacement chicks less than 14 days before egg laying starts, as the active ingredients of the drug accumulates there.

    Avoid using Amoxigard WS concurrently with other penicillin family drugs, chloramphenicol, macrolides, sulfonamides, and tetracyclines

  • Restrictions
  • Restrictions

    Pigs can be slaughtered for human consumption not earlier than 3 days, poultry - not earlier than 7 days after Amixygard WS was administered for the last time. In the case of forced slaughter of animals and poultry before the established deadlines, the meat can be used for feeding carnivores.

    SHELF LIFE

    3 years from the date of manufacture; after first opening - 7 days

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