Amoxicillin 150

Amoxicillin trihydrate, the active substance of Amoxicliliin 150, is a semisynthetic penicillin-type antibiotic with a broad spectrum of antimicrobial activity. The mechanism of action of the drug is as follows: it disrupts the process of mucopeptide (a component of microbial cell wall) synthesis by inhibiting transpeptidase and carboxypeptidase activity, which leads to disruption of osmotic balance and destruction of the microbial cell. Amoxicillin is very effective against most Gram-positive and Gram-negative microbes including: Actynomyces spp., Bacillus anthracis, Clostridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Staphylococcus spp., Escherichia coli, Haemophilus spp., Pasteurella spp., Salmonella spp., Streptococcus spp, Actinobacillus spp., Proteus mirabilis, Leptospira spp.

Following parenteral injection, amoxycilline trihydrate concentration reaches its peak after 1-2 hours and remains at therapeutic level for 48 hours. The antibiotic is eliminated mostly unchanged with urine and feces 

Amoxicillin 150 is used for treatment of cattle, sheep and swine infectious diseases of the gastrointestinal tract, respiratory tract, urogenital system, joints, soft tissues and skin, necrobacteriosis, umbilical infections, atrophic rhinitis, mastitis-metritis-agalactia syndrome, and other primary and secondary bacterial infections, the causative agents of which are sensitive to amoxicillin.

Slaughter of animals for meat is permitted not earlier than 28 days after the last injection of Amoxicillin 150. The Meat from animals, forcedly slaughtered before the expiry of this period, may be used as feed for fur animals. The Milk from lactating animals may be used for food no earlier than 4 days after the last injection. The Milk obtained during treatment and within 4 days after the last injection may be used for animal feed after boiling.