Lexoflon

Reliable barrier
Cattle
Swine
Levofloxacin

A broad-spectrum antibiotic for pigs and cattle with short restrictions on milk

Designed for dairy animals

An alternative for rotation with cephalosporins

Overcomes resistance to enrofloxacin

  • Description
  • An antibiotic of the new generation of fluoroquinolones with a wide range of action for treatment of diseases of cattle and pigs.

    Appearance: a clear greenish-yellow to yellow solution.

    Lexoflon® is available in 100 mL glass vials closed with rubber stoppers and sealed with aluminum caps with tamper proof clamps.

  • Composition
  • Composition
    1 ml Lexoflon = 150 mg levofloxacin
  • Pharmacological properties
  • Pharmacological properties

    As a new generation agent, levofloxacin allows overcoming the microorganisms’ resistance to previous generations fluoroquinolones, including Enrofloxacin.

    Levofloxacin penetrates well into the organs and tissues, thus is quickly and almost completely absorbed after parenteral administration. The bioavailability of the active substance is 99%, the concentration in serum reaches its peak within 2 hours after administration, the elimination half-life is 7 hours.
    Lexoflon is used in cattle and pigs for treatment of bacterial diseases of the respiratory system, digestive system, obstetric and gynecological diseases (metritis and mastitis), postpartum infections in sows (metritis, mastitis, agalactia), surgical diseases and soft tissue infections (such as abscesses, phlegmon, etc.) caused by pathogens sensitive to levofloxacin, including aerobic Gram-positive microorganisms: Enterococcus spp, Listeria monocytogenes, Staphylococcus spp. (including Staphylococcus aureus), Streptococcus spp; aerobic Gram-negative microorganisms Acinetobacter spp, Campylobacter spp, Enterobacter spp, Escherichia coli, Haemophilus ducreyi, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella spp, Moraxella catarrhalis β+/β-, Morganella morganii, Pasteurella spp, Proteus mirabilis, Proteus vulgaris, Providencia spp, Pseudomonas spp, Salmonella spp, Serratia spp.; anaerobic microorganisms Bacteroides fragilis, Clostridium perfringens, Fusobacterium spp, Peptostreptococcus; other microorganisms: Chlamydia pneumoniae, Chlamydia psittaci, Mycobacterium spp, Mycoplasma pneumoniae, and Ricketsia spp.

  • Indications
  • Indications

    As a new generation agent, levofloxacin allows overcoming the microorganisms’ resistance to previous generations fluoroquinolones, including Enrofloxacin.

    Levofloxacin penetrates well into the organs and tissues, thus is quickly and almost completely absorbed after parenteral administration. The bioavailability of the active substance is 99%, the concentration in serum reaches its peak within 2 hours after administration, the elimination half-life is 7 hours.
    Lexoflon is used in cattle and pigs for treatment of bacterial diseases of the respiratory system, digestive system, obstetric and gynecological diseases (metritis and mastitis), postpartum infections in sows (metritis, mastitis, agalactia), surgical diseases and soft tissue infections (such as abscesses, phlegmon, etc.) caused by pathogens sensitive to levofloxacin, including aerobic Gram-positive microorganisms: Enterococcus spp, Listeria monocytogenes, Staphylococcus spp. (including Staphylococcus aureus), Streptococcus spp; aerobic Gram-negative microorganisms Acinetobacter spp, Campylobacter spp, Enterobacter spp, Escherichia coli, Haemophilus ducreyi, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella spp, Moraxella catarrhalis β+/β-, Morganella morganii, Pasteurella spp, Proteus mirabilis, Proteus vulgaris, Providencia spp, Pseudomonas spp, Salmonella spp, Serratia spp.; anaerobic microorganisms Bacteroides fragilis, Clostridium perfringens, Fusobacterium spp, Peptostreptococcus; other microorganisms: Chlamydia pneumoniae, Chlamydia psittaci, Mycobacterium spp, Mycoplasma pneumoniae, and Ricketsia spp.

  • Dosage and route of administration

    Lexoflon is administered intramuscularly in the following doses: cattle and pigs: 1.0 mL per 30 kg of body weight (5.0 mg of levofloxacin per 1 kg of body weight) daily for 3-5 days.

  • Dosage and route of administration
  • Dosage and route of administration

    Lexoflon is administered intramuscularly in the following doses: cattle and pigs: 1.0 mL per 30 kg of body weight (5.0 mg of levofloxacin per 1 kg of body weight) daily for 3-5 days.

  • Restrictions
  • Restrictions

    Milk can be used for food purposes not earlier than 96 hours after the last use of Lexoflon. Milk, obtained before the expiration of the specified period, can be used for feeding animals after heat treatment. Slaughter for meat of cattle and pigs is carried out not earlier than 9 days after the last injection of the drug. Meat from animals slaughtered before the expiration of the specified term, may be used to feed carnivorous animals.

  • Publications
  • Publications
  • Treatment regimen

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