Amoxygard

Enhanced amoxycillin
Cattle
Small cattle
Swine
Аmoxicillin, clavulanic acid

A reliable amoxicillin- and clavulanic acid based veterinary drug, which works against the resistance to β-lactam antibiotics

Works against the resistance to beta-lactam antibiotics

A highly effective therapy

“A new life” of one of the most popular antibiotics

  • Description
  • A reliable drug for treatment of animals based on amoxicillin and clavulanic acid that works against the resistance to β-lactam antibiotics.
    Appearance: a white to yellow oily suspension. During storage, phase separation may occur. It disappears when shaking.
    The drug is packaged in 100 mL sealed vials.

  • Composition
  • Composition
    1 ml Amoxygard = 140 mg amoxicillin and 35 mg clavulanic acid
  • Pharmacological properties
  • Pharmacological properties

    Amoxygard is a combined antibacterial drug with a broad-spectrum antibacterial activity against most Gram-positive and Gram-negative microorganisms, including β-lactamase-producing strains: Staphylococcus spp., Streptococcus spp., Corynebacterium, Clostridium, Bacillus anthracis, Actinomyces bovis, Peptostreptococcus spp., Escherichia coli, Salmonella, Bordetella bronchiseptica, Campilobacter spp., Klebsiella, Proteus spp., Pasteurella, Fusobacterium necrophorum, Bacteroides, Haemophilus spp., Moraxella spp., Actinobacillus pleuropneumoniae, and Actinobacillus ligneresi. Resistance to β-lactam antibiotics is usually associated with the microorganisms’ ability to produce β-lactamase, an enzyme that breaks down the β-lactam ring of the antibiotic before it can affect the bacterium. Clavulanic acid contained in Amoxygard inactivates β-lactamase and thus restores the bacterial sensitivity to the bactericidal action of amoxicillin at concentrations that are easily achieved in the animal tissues upon the injection.


  • Indications
  • Indications

    Amoxygard is a combined antibacterial drug with a broad-spectrum antibacterial activity against most Gram-positive and Gram-negative microorganisms, including β-lactamase-producing strains: Staphylococcus spp., Streptococcus spp., Corynebacterium, Clostridium, Bacillus anthracis, Actinomyces bovis, Peptostreptococcus spp., Escherichia coli, Salmonella, Bordetella bronchiseptica, Campilobacter spp., Klebsiella, Proteus spp., Pasteurella, Fusobacterium necrophorum, Bacteroides, Haemophilus spp., Moraxella spp., Actinobacillus pleuropneumoniae, and Actinobacillus ligneresi. Resistance to β-lactam antibiotics is usually associated with the microorganisms’ ability to produce β-lactamase, an enzyme that breaks down the β-lactam ring of the antibiotic before it can affect the bacterium. Clavulanic acid contained in Amoxygard inactivates β-lactamase and thus restores the bacterial sensitivity to the bactericidal action of amoxicillin at concentrations that are easily achieved in the animal tissues upon the injection.


  • Dosage and route of administration

    Amoxygard shall be administered in animals in a dose of 1 ml per 20 kg of animal body weight. The drugs shall be administered once daily; the treatment session is typically for 3 to 5 days. Before each application, thoroughly shake a vial of Amoxygard till formation of homogenous suspended mixture. The drugs shall be administered in cattle and pigs intramuscularly only. The site of injection, upon the drug administration, should be massaged.

    Only dry syringes and needles shall be used for the drug administration.     

    Amoxygard as compared to a foreign amoxicillin-based monotherapy

    The following results have been obtained, when comparing Amoxygard with expensive foreign amoxicillin-based monotherapies:

    Indicator

    Amoxygard

    Foreign amoxicillin-based monotherapy

    Number of calves

    150

    40

    Number of injections

    3

    3

    Visible effect, h

    18

    28

    Recovery period, h

    72

    108


  • Dosage and route of administration
  • Dosage and route of administration

    Amoxygard shall be administered in animals in a dose of 1 ml per 20 kg of animal body weight. The drugs shall be administered once daily; the treatment session is typically for 3 to 5 days. Before each application, thoroughly shake a vial of Amoxygard till formation of homogenous suspended mixture. The drugs shall be administered in cattle and pigs intramuscularly only. The site of injection, upon the drug administration, should be massaged.

    Only dry syringes and needles shall be used for the drug administration.     

    Amoxygard as compared to a foreign amoxicillin-based monotherapy

    The following results have been obtained, when comparing Amoxygard with expensive foreign amoxicillin-based monotherapies:

    Indicator

    Amoxygard

    Foreign amoxicillin-based monotherapy

    Number of calves

    150

    40

    Number of injections

    3

    3

    Visible effect, h

    18

    28

    Recovery period, h

    72

    108


  • Restrictions
  • Restrictions

    Milk can be used for food purposes not earlier than after 80 hours after the last treatment. Milk that is obtained before the expiration of the specified period, may be used for animal feed after thermal treatment. Slaughter of animals for meat is permitted not earlier than after 14 days. Meat from animals forcedly slaughtered before the expiry of the specified period may be used for feeding fur animals or for the production of meat and bone flour.

  • Publications
  • Publications
  • Treatment regimen

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